Senior Controls Engineer (I,II,III) - HMI



South San Francisco, CA, USA
Posted on Wednesday, February 7, 2024
Position Summary
We are seeking an innovative and highly motivated controls engineer who will contribute significantly to the development of our advanced cell therapy manufacturing platform.
The primary focus of this position will be the design, implementation, and test/verification of Human Machine Interfaces for our hardware platform. You will meet with stakeholders to understand user requirements and implement the server architecture and frontend user interfaces for the equipment. You must be comfortable working with modern web-based HMI products, scripting in Python, and basic server and database management. In your role, you may also be tasked with development of PLC code for equipment, design of test fixtures, and be responsible for other equipment related development activities. This individual will interface across many parts of the company to develop novel products used in the cell therapy and gene therapy world.
Candidates should enjoy working in a fast-paced, mission-driven environment, and be prepared to tackle a broad selection of challenges as the company grows.


  • Lead the development of HMI and SCADA systems using the Ignition Perspective product, with attention paid to simplicity, clean layouts, and ease-of-use
  • Work with IT/OT to manage HMI servers, implement monitoring, and perform software updates and deployments when required
  • Create basic database schemas, manage database infrastructure, and write SQL queries with attention paid to the performance of queries
  • Develop PLC control software using Structured Text and leveraging object oriented programming methodologies
  • Develop unit tests and functional tests for PLC code that you write, participate in code reviews, and leverage Git for version control and code management
  • Participate in design reviews and provide input to identify issues and drive design choices
  • Collaborate with the software team to develop robust, well documented software interfaces to hardware
  • Collaborate with external stakeholders including Systems Engineering, Quality, Mechanical Engineering, Process Development, etc. for project planning, requirements development, and architecture development
  • Develop test software in Python, C# or other languages to validate subsystems during manufacture, and to implement more advanced functions in the HMI


  • Bachelors or Masters degree in Computer Engineering, Computer Science, Software Engineering, Electrical Engineering or equivalent experience is required
  • 5+ years industry experience developing control systems for customer-shippable life science instrumentation or comparable equipment, including HMI and SCADA development
  • Experience with at least one major PLC platform (Siemens TIA Portal, Beckhoff TwinCAT3, B&R)
  • Proficient working with Ignition, Indusoft, Wonderware, or similar HMI products
  • Comfortable following change control practices in a regulated GMP environment
  • Experience creating basic SQL schemas, writing SQL queries, troubleshooting poorly performing queries, and developing dashboards and other visualizations
  • Proficient with IEC 61131-3 based languages with a focus on Structured Text
  • Proficient with object-oriented programming and have an understanding of how to apply OOP concepts to control software
  • Experience with fieldbus technologies such as EtherCAT, Profinet, EtherNet/IP
  • Experience with the Python programming language
  • Desire to work in a fast-paced, collaborative start-up environment
  • Self-awareness, integrity, authenticity, and a growth mindset

Nice to Have

  • Prior experience working in a regulated environment, including following change control practices
  • Prior experience managing virtualized infrastructure such as VMWare vSphere
This is Cellares
Cellares is the first Integrated Development and Manufacturing Organization (IDMO) and takes an Industry 4.0 approach to mass manufacturing the living drugs of the 21st century. The company is both developing and operating integrated technologies for cell therapy manufacturing to accelerate access to life-saving cell therapies. The company’s Cell Shuttle integrates all the technologies required for the entire manufacturing process in a flexible and high-throughput platform that delivers true walk-away, end-to-end automation. Cell Shuttles will be deployed in Cellares’ Smart Factories around the world to meet total patient demand for cell therapies at global scale. Partnering with Cellares enables academics, biotechs, and pharma companies to accelerate drug development and scale out manufacturing, lower process failure rates, lower manufacturing costs, and meet global patient demand.
The company is headquartered in South San Francisco, California with its commercial-scale IDMO Smart Factory in Bridgewater, New Jersey. The company is backed by world-class investors and has raised over $355 million in financing.
Leveling will be based on overall experience, education, and demonstration of knowledge throughout the interview process.